I will not go here in details how bad is trigeminal neuralgia, I think majority of us know how dreadful is stabbing pain in the face, behind the ear and on top of the head. And especially when this pain does not subside or returns again after traditional therapy with Diclofenac and Gabapentin. Also main part of my colleagues will increase the dosage of Gabapentin, let say if 600 mg is not helpful, then take 900 or 1200 mg which I consider absurd, because Gabapentin is not innocent medication and also it gives resistance, means that small dosages stop to be helpful and sometimes big ones too. Diclofenac from other hand is also harmful. It destroys the stomach and also body gets used to it, but to increase dosage of Diclofenac is not easy and basically typically all ends by prescribing drugs. Which leads to fatal consequences, dependency and literally end of life. Another story is about malformation when nerve meets wall of skull or/ and artery or vein- this syndrome called sandwich. Usually treatment is same as above or surgery- let's divide and put bridge. 85% of these surgeries end with post-operative pain, because to divide artery from nerve it is very complicated and usually they put bridge between them, so it is a foreign body, which brings other type of pain.
I am calling it vicious circle.
But there is light in the end of tunnel.
As usually plants are our cure and everything genius is quite simple.
And as mentioned above all new is long time forgotten old.
So let start with main principles. We need to have analgesic, which must be antinociceptive- very nice word, which means basically anti inflammatory ,but in very delicate way. So it means that sensory neurons are being disturbed by some stymuli, such toxic, temperature, pressure (mechanic) etc and this pain actually sort of protects tissue by further damage so all we need to do to stop the trigger. However if we do not do anything about it, then it can go further to tissue damage and then this pain is inflammatory and goes with different scenario and subsides only after tissue repair. If we follow this idea it means that all pain which related to nerves belongs to nociceptive at least from the beginning. Therefore if we realize it in time then we can easy manage it without heavy medications. And stop it from the beginning and of course also prevent further inflammation if such factors exist (i.e viruses, bacteria and other pathogens).
The first and the most oldest medication used for this matter is Milgamma (yep- old McDonald had a farm.....children song) and in particular vitamins of B group- these famous three friends. Tiamin Vitamin B1, Piridoxin or Vitamin B6 and finally Cyanocobalamin or Vitamin B12. So even one by one all these have antinociceptive effect and were used and still are used for all kinds of neuropathies.
To read about them you can all over. One small remark that to use vitamins of Group B you can only limited times because they have cumulative effect in the body and overdose also can bring trouble, in particular Piridoxin itself can give sensory neuropathy if taken more than 3 months and in high dosages. But obviously everything needs to be taken within limits. 14 days usually it is more the enough to treat stubborn neuralgia, but can be taken until 21 days.
In acute situation it is recommended to start with injections and then continue in tablets.
Their favorable effect also that they potent Diclofenac ,Dexamethasone and Magnesium (especially orotate ,bysglicinate and sulfate). So basically you can stop severe nerve pain very quickly if you add any Vitamin B either B1, B6 or B12 of this company. But of course it is better to have them together as Milgamma N.
Now we come to my favorite part.
We have replacement for Diclofenac and it is famous Boswellia . You can read about it in one of my previous articles. But I can tell you more in addition to Boswellia you can take simple plant Rosemary (Rosmarinus officinalis). Yes the one which usually very good goes to a cooking with potatoes and meat. Rosemary has potent anti inflammatory and antinociceptive effect and it is a friend with Boswellia and actually can act alone. But it was noticed that it goes well with Ketoprofen (relative of Diclofenac) and together this combination is equal to power of Morphine. Also Rosemary has anxyolitic and sedative effect and it acts like Diazepam ,so basically you do not need to suffer anymore, because not only it cures acute pain but it prevents it too. Rosemary has many other nice bonuses, such antidepressant, hepatoprotective and neuroprotective effects, which means it can repair damaged neurons and reverse ischemia. It protects your vision too- in particular it prevents macular degeneration
Some details you can see here- it is miraculous, yes and basically you do not need much of it . 700 mg and no pain,no anxiety ,effect lasts long.
Of course also about Rosemary works principle do not exaggerate. Rosemary cant be taken if your have hypertension since it increases the blood pressure, In the meantime it has diuretic effects so it cant be taken with diuretics and it interacts with Lithium, so these people with manic depression must be cautious. Or Rosemary or Lithium, but not both. Usage in pregnancy is prohibited can cause miscarriage. Toxicity starts from single dosage above 2 gr per kg with side effects of nausea, vomiting and if dosage goes up then confusion and coma.
And finally we reach end of the list and nucleotide. Sounds terrible, but in fact its are old neuroprotective substances, which we do have in our body too. A little bit. And these substances basically can fully replace conventional medications such Diclofenac and ko.
Because they have strong anti inflammatory ,anti nociceptive and neuroprotective abilities. One of them is Uridine. Another one is Cytidine and they like Vitamin B12 to be added for full power. Uridine can be taken alone also applied topically. As per my personal experience dosage 250 mg stops acute pain in 20 min and effect remains steady for 12-24 hrs.
If it is taken with Cytidine and Vit.B12, Boswellia and Rosemary it is equivalent to combination of Morphine and Diazepam and can be used in acute trauma . In my case it was used for patient with shoulder fracture. Uridine 250 mg with Vit.B12 1 mg and Boswellia 800 mg with topical mixture of Uridine, Boswellia, Symphitum officinalis and shea butter, fully stopped the pain. The patient was elderly so Rosemary was not given.
Uridine has also anticonvulsant effect, so can be given to prevent epilepsy.
It can be used in all types of nerve damages and the earliest improvement was seen in 4 days (total disappearance of sciatic pain ) and the usual indication is 14-21 days course.
Comments