New research was made recently and it was found that the cause of cystic acne can be caused also by increased cholesterol and not only due to progesterone- estrogen- testosterone broken relations.
The control group of young females and males( 54/67) with increased LDL and total cholesterol were taking Niacin *B3 vitamin* 50 mg once daily for 3 months with control of HDL, LDL, total cholesterol and lipid profile every 1 month, were shown good response.
From 54 females with age from 15.yo to 50 y.o 45 females got significant reducing of LDL and total cholesterol as well increasing HDL and clearing skin.
From 67 males - 58 got the same result as well improved peripheral circulation (especially those with diabetic neuropathy), decreasing TA and improving reology of blood.
Niacin is old medication which has specific immediate effect as red skin rash and feeling of heat flush for first 15 min since intake .It is due to dilatation of all blood vessels and is not allergic reaction of adverse effect. So no need to go in panic or to cancel it. After 3 days usually the body gets adapted and the effect is decreasing and becomes insignificant.
Niacin is recommended to be taken with food or after food. When hot flash appears 1-2 glasses of water help to diminish unpleasant feeling.
Reference : https://www.ncbi.nlm.nih.gov/pubmed/20880492/
https://onlinelibrary.wiley.com/doi/pdf/10.1111/1346-8138.12761
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